Authors: OTSUKA, YUICHI; KONISHI, TOSHIRO1; NARA, SATOSHI1; FURUSHIMA, KAORU1; NAKAJIMA, KENTARO1; SHIMADA, HIROSHI2 Source: Journal of Gastroenterology and Hepatology, Volume 20, Number 9, September 2005 , pp. 1318-1321(4) Publisher: Blackwell Publishing A 50-year-old man was referred to our... 

—      Istituto Nazionale Tumori, Milan (S. V., E. N., A. O., G. S., A. S.); Chair of Chemotherapy, University of Milan, (P. L., G. E., F. F.) Italy Experimental studies have suggested that the pineal hormone melatonin, in addition to its documented antineoplastic action, plays a role in the... 

Although p53 mutations occur in alkylating agent-related leukemias, their frequency and spectrum in leukemias after ovarian cancer have not been addressed. The purpose of this study was to examine p53 mutations in leukemias after ovarian cancer, for which treatment with platinum analogues was widely... 

Severe, often refractory anemia is characteristic of the myelodysplastic syndrome associated with chromosome 5q31 deletion. We investigated whether lenalidomide (CC5013) could reduce the transfusion requirement and suppress the abnormal 5q31– clone in patients with this disorder. Methods One hundred...